Just to weigh in with more feelings on this, which mirror the first couple of paragraphs of the above comment, sadly without their change of heart. IMHO, even if a genderfluid/non-conforming reading of Crowley might be considered valid through word of god or other interpretations, I'm having a hard time swallowing his inclusion in this particular exchange, specifically because of his overwhelming presence in fandom as one half of a significant and massively popular M/M ship.

Basically, while there may be leeway for a genderfluid interpretation of Crowley, his existence and presence in fannish spaces is so overwhelmingly and inextricably tied to M/M, I think that should be something to take into account for this particular case, given the nature of this exchange.